ISO 19040-1:2018
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ISO 19040-1:2018
64450
недоступно на русском языке

This document specifies a method for the determination of the estrogenic potential of water and waste water by means of a reporter gene assay with genetically modified yeast strains Saccharomyces cerevisiae. This reporter gene assay is based on the activation of the human estrogen receptor alpha.

This method is applicable to:

— fresh water;

— waste water;

— aqueous extracts and leachates;

— eluates of sediments (fresh water);

— pore water;

— aqueous solutions of single substances or of chemical mixtures;

— drinking water.

The limit of quantification (LOQ) of this method for the direct analysis of water samples is between 8 ng/l and 15 ng/l 17β-estradiol equivalents (EEQ) based on the results of the international interlaboratory trial (see Annex F). The upper threshold of the dynamic range for this test is between 120 ng/l and 160 ng/l 17β-estradiol equivalents (EEQ). Samples showing estrogenic potencies above this threshold have to be diluted for a valid quantification. Extraction and pre-concentration of water samples can prove necessary, if their estrogenic potential is below the given LOQ.


Общая информация 

  •  :  Published
     : 2018-08
  •  : 1
  •  : ISO/TC 147/SC 5 Biological methods
  •  :
    13.060.70 Examination of biological properties of water

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Формат Язык
std 1 178 PDF
std 2 178 Бумажный
std 3 178 PDF + ePub
  • CHF178

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